Tropilab Inc.
CURCUMIN TEA
 (Infusion CURCUMA XANTHORRHIZA)

from AMAZON HERBS®



Curcuma xanthorriza Overview

Traditionally, the rhizomes of Curcuma longa and Xanthorriza (spices), from the Zingeberaceae family have been used as a remedy for liver problems and indigestion.
They have also been used against internal parasites in traditional medicine.
CURCUMA XANTHORRHIZA is also known as Javanese turmeric.

 Constituents

Curcuminoids* (curcumin, dicinnamoyl - methane,bis - demethoxy - curcumin, demethoxy curcumin).
Terpenoids (sesgueterpenoids, monoterpenoid), Xanthorrhizol (sesquiterpenoid). Essential oils (camphor, isofurano - germacrese, cineo, borneol).
Major volatile components: 1,8-cineol and curzerenone.
Cinnamaldehyde.
Starch / carbohydrate (30% - 40%).
Curcuma xanthorriza contain 6 - 11 % of 1 - cyclo iso prene myrcene essential oil.

 Pharmacology

Curcumin has been proven to exhibit anticarcinogenic, anti-inflammatory and antioxidant properties, it stimulates the immune functions of macrophages.
Curcumin main application is as an anti-inflammatory herbal drug that produces far fewer side effects than commonly used pain relievers.
This inflammation includes those caused by arthritis, swelling pain, muscle sprain, surgical incisions.
In addition, it lowers LDL cholesterol and is able to cure hepatitis (broad spectrum hepatoprotective agent).
When used for the cancer fighting capabilities, it shows a remarkable effect in intervening with initiation and growth of cancer cells and tumors.
It inhibits the progression of chemically induced colon and skin cancers.
Curcumin has been shown to enhance the effectiveness of certain, anti cancer drugs and also improve the effectiveness of radiation treatment.
The tumor cells are prevented from developing the so called radiation resistance.
Curcumin can both prevent - and treat cancer. It suppresses LOX 2, NOS MMP 9 and COX (these are enzymes that make carcinogens much more active once they are in the body; they also allow cancerous cells to grow new blood vessels). The area of the kinase inhibitors is a hot area of oncology drug development. There are many of these protein kinases and they act as message lines into the DNA command center of the cells. Curcumin can effectively blocks a number of these lines. It has the ability to prevent skin cancer, is effective against colon cancer, it also enhances immunity and stops angiogenesis (ability to enable tumors to create an own blood supply).
Xanthorrhizol (a sesquiterpenoid compound isolated from the rhizome), exerts anti-metastatic activity in vivo.
A recent study suggests that combination of curcuminoids, essential oils of C. domestica and C.xhantorrihizza, have anti-inflammatory effects comparable to Piroxicam (Feldene), a known anti-inflammatory agent.

 Applications

Kidney disease, high cholesterol, hypertension, appetite loss, gallbladder problems, malaria, Alzheimer's disease, prevention and treatment of cancer, potentiate the effect of chemotherapy, ulcers, liver disease, jaundice, injuries, arthritis, chemotherapy, bursitis, prostatits, cystic fibrosis.
Curcumin kills cancer cells long before they can be detected; it induces cancer cell apoptosis (cell suicide)

 Part used
Rhizome; only wild harvested - or organically grown plants, naturally derived alcohol (USP) and spring water are used. Curcumin rhizome powder (1:4) in an alcohol - and spring water solution (alcohol 50% v / v).

 Dosage

Against cholesterol: 1, 5 - 2 ml. (45 - 60 drops), 3 - 4 times daily.
Cancer: 2000 - 4000 mg / powder daily.
Other applications:
Tincture: 1½ - 2 ml.
Infusion: 1 - 2 cups daily.

 Precaution

Side effects and / or interactions
Turmeric is "generally recognized as safe" (GRAS), as a food additive by the FDA and serious adverse effects have not been reported in humans taking high doses of Curcumin.
If you take medications or undergo chemo- and / or radiotherapy for treating cancer, be cautious about possible interactions of Curcumin. Consult your oncologist and radiologist.
Patients with gallstones, bile duct obstruction, stomach ulcers and hyperacidity disorders should refrain from taking this herbal supplement.
As a precautionary measure, curcumin should not be used during pregnancy unless under supervision of a physician.
Anticoagulants / antiplatelets: Curcumin may increase risk of bleeding.
When using non-steroidal pain relievers ((Ibuproven), avoid Curcumin.

 Reference

 United States Patent 5120538.
http://www.freepatentsonline.com/5120538.html
This invention relates to naturally occurring pharmaceutical compositions, more particularly, those compositions of compounds isolated from the plant genus Curcuma, which are useful as anti-inflammatory agents.
Chan MM, Fong D, Soprano KJ, Holmes WF, Heverling H. Inhibition of growth and sensiti- zation to cisplatin-mediated killing of ovarian cancer cells by polyphenolic chemopreventive agents. J Cell Physiol. 2003 Jan;194(1):63-70.
Bharti AC, Donato N, Singh S, Aggarwal BB. Curcumin (diferuloylmethane) down-regu- lates the constitutive activation of nuclear fac- tor-kappa B and IkappaBalpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis. Blood. 2003 Feb;101(3):1053-62.
Aggarwal BB, Kumar A, Bharti AC. Anticancer potential of curcumin: preclinical and clinical studies. Anticancer Res. Jan-Feb 2003;23(1A):363-98.
Medicinal foodstuffs. XXIX. Potent protective effects of sesquiterpenes and curcumin from Zedoariae Rhizoma on liver injury induced by D-galactosamine/lipopolysaccharide or tumor necrosis factor-alpha.
Morikawa T, Matsuda H, Ninomiya K, Yoshikawa M.
Kyoto Pharmaceutical University, Japan.

 The above presentation is for informational and educational purposes only.
It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage.
For many of the conditions discussed, treatment with prescription or over - the - counter medication is also available.
Consult your doctor, practitioner, and / or pharmacist for any health problem and before using dietary supplements or before making any changes in prescribed medications.
Buy 6 bottles save 10%; buy 12 bottles and save 15%!
Item Description Unit Price Quantity
Curcumin xanthorriza tincture 1 fl. oz (29.6 cc) U$ 10.35
Curcumin xanthorriza tincture 6 x 1 fl. oz U$ 55.89
Curcumin xanthorriza tincture 12 x 1 fl. oz U$ 105.57
Curcuma xanthorriza tincture 2 fl. oz (59.1 cc) U$ 18.65
Curcuma xanthorriza tincture 6 x 2 fl. oz U$ 100.71
Curcuma xanthorriza tincture 12 x 2 fl. oz U$ 190.23
Curcuma xanthorriza powder 1 lb U$ 24.00
Curcuma xanthorriza powder 5 lbs U$ 103.55 (20.71 / lb)
Curcuma xanthorriza powder 10 lbs U$ 185.30 (18.53 / lb)
Curcuma xanthorriza powder 22.2 lbs U$ 338.79 (15.26 / lb)




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References:
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  • Recent studies found that curcumin has a doce - dependent chemopreventive effect in rats during promotion / progression stages of colon cancer
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  • Tufts researchers say "a mixture of curcumin and isoflavonoids is the most potent inhibitor against the growth of human breast tumor cells". These data suggest that combinations of natural plants compounds may have preventive and therapeutic applications against the growth of breast tumors induced by environmental estrogens (Environ Health Prspect 1998 Dec; 106 (12): 807 - 12).

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  • Yasni S, Yoshiie K, Oda H, Sugano M, Imaizumi K. Dietary curcuma xanthorriza roxb. increases mitogenic responses of splenic lymphocytes in rats and alters populations of the lymphocytes in mice.



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